International Conference · 2027

Unwinding the
biology of helicases.

Join our community of mechanistically minded researchers studying nucleic acid translocation, unwinding, and modification, with implications for genome integrity, aging, and disease.

Save the Date
June 20-23, 2027
Montréal, Canada
Québec
140 participants
Intimate, focused audience
Dates
Jun 20 – 23, 2027
Location
Montréal, Canada
Attendees
≈ 140 researchers
Format
Talks · Posters · Keynote
Our Conference

Mechanistic discoveries in nucleic acids machines.

The Helicases and Nucleic Acid-Based Machines conference brings together researchers working on macromolecular machines that drive DNA replication, chromatin organization, repair, transcription, Nucleic acid-based immunity, RNA structural reorganization and processing and RNA-guided processes. Defects in these machines underlie a broad spectrum of human diseases, from premature aging and cancer susceptibility to immunodeficiency and developmental disorders. The meeting integrates biochemistry, structural biology, biophysics, and cell biology to highlight mechanistic discoveries, emerging technologies, and the work of early-career scientists alongside established leaders in the field.

Plan to join us in Montréal!

AP
Opening Keynote
Anna Pyle
Yale University, New Haven, Connecticut, USA
Professor Pyle's pioneering work on RNA helicases, group II intron catalysis, and RIG-I based RNA-sensing immunity has shaped our understanding of how RNA is folded, remodeled, and read. She opens the 2027 meeting with a keynote lecture.
JB
Closing Keynote
James M. Berger
Johns Hopkins, Baltimore, Maryland, USA
Professor Berger’s influential studies of ATPase enzymes have shaped our thinking of DNA replication initiation, topology changes, and chromatin maintenance. He will close the 2027 meeting with a keynote lecture.
Invited
Speakers
01
Franziska Bleichert
Yale University
02
Markus Bohnsack
University of Göttingen
03
Zhucheng Chen
Tsinghua University
04
Tom Deegan
University of Edinburgh
05
Dmitry Ghilarov
University of Oxford
06
Leemor Joshua Tor
Cold Spring Harbor Laboratory
07
James Keck
University of Wisconsin–Madison
08
Caroline Kisker
University of Würzburg
09
Fernando Moreno Herrero
CNB-CSIC, Madrid
10
Sua Myong
Harvard Medical School
11
Christof Niehrs
IMB, Mainz
12
Katrin Paeschke
University of Bonn
13
Kevin Raney
University of Arkansas for Medical Sciences
14
Dirk Remus
Harvard Medical School
15
David Rueda
Imperial College London
16
Dipali Sashital
Iowa State University
17
Agata Smogorzewska
The Rockefeller University
18
Maria Spies
University of Iowa
Program Committee
Conference Organizers
Alessandro Costa
The Francis Crick Institute, London, United Kingdom
Ailong Ke
Yale University, New Haven, Connecticut, USA
Danzhou Yang
Purdue University, West Lafayette, Indiana, USA